Methyl-L-NIO hydrochloride

Overview

Methyl-L-NIO (compound 2d) hydrochloride is a potential selective inhibitor ( IC 50 : 70 μM) of dimethylarginine dimethylaminohydrolase hDDAH. Methyl-L-NIO also has inhibitory activity against NO synthase . The inhibition rates of Methyl-L-NIO on different isoforms of NO synthase at a concentration of 100 μM are 77% ( nNOS ), 20% ( eNOS ), and 72% ( iNOS ) respectively; the inhibition rates at a concentration of 1 mM are 100% ( nNOS ), 85% ( eNOS ), 100% ( iNOS ).

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-139135
• CAS No.: 150403-96-6
• Molecular Formula: C8H18ClN3O2
• Molecular Weight: 223.70
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source