Larsucosterol (DUR-928) sodium, a cholesterol metabolite, is a potent liver X receptor ( LXR ) antagonist. Larsucosterol sodium as a potent endogenous regulator decreases lipogenesis. Larsucosterol sodium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > LXR | Products > Signaling Pathways > Endogenous Metabolite
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