FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins ( PBP s).FPI-1465 inhibits PBP2 ( IC 50 =1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with K d s of 0.011 and 5.3 µM, respectively.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Penicillin-binding protein (PBP) | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Bacterial
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