SCH-39370 is a potent and specific inhibitor of neutral metalloendopeptidase ( NEP ) from rabbit kidney with an IC 50 value of 11.2 nM. SCH-39370 potentiates biological responses to atrial natriuretic factor and lowers blood pressure in desoxycorticosterone acetate-sodium hypertensive rats.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Prolyl Endopeptidase (PREP) | Products > Signaling Pathways > Neprilysin
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