N-Acetyl-D-Glucosamine

N-Acetyl-D-Glucosamine
  • CAS No.:7512-17-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :

Melting point 211 °C (dec.) (lit.)
alpha 42 º (c=2,water,2 hrs)
refractive index 40.5 ° (C=1, H2O)
storage temp. -20°C
solubility H2O: 50 mg/mL colorless to faint yellow solution, clear to very slightly hazy
pKa13.04±0.20(Predicted)
Boiling point 636.4±55.0 °C(Predicted)
density 1.54 g/cm3
form saline suspension
color white to off-white
Water Solubility Soluble in concentrated hydrochloric acid, sulfuric acid, phosphoric acid and formic acid. Insoluble in water, dilute acids, dilute alkalis, concentrated alkalis and organic solvents.
Sensitive Hygroscopic
Merck 14,4458
BRN 1727589
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyOVRNDRQMDRJTHS-ROGOILFBSA-N
CAS DataBase Reference7512-17-6(CAS DataBase Reference)
EPA Substance Registry SystemN-Acetylglucosamine (7512-17-6)
ActiBiso-NAG is the basic unit of many important polysaccharides in biological cells and has many important physiological functions in organisms. Acetyl glucosamine is a small molecular amino monosaccharide obtained by biological fermentation. It has excellent percutaneous absorption and can improve the hydration ability of skin. It is a high-quality multifunctional moisturizer, widely used in various cosmetic formulation systems. 

1. The moisturizing- Acetyl glucosamine in colleges has excellent absorption through the skin, can promote the hydration of the skin, and is an efficient moisturizer.    
        
2. Promote the synthesis of hyaluronic acid in the skin - enhance the activity of hyaluronic acid synthetase (HAS), promote the synthesis and secretion of hyaluronic acid by keratinocytes and fibroblasts, and increase the content of hyaluronic acid in the skin.

3. Natural keratinocyte regulator - natural keratinocyte regulates and maintains the normal metabolism of surface keratinocyte. The unhealthy metabolism of keratinocyte makes its glycoprotein on surface tangle together, which is not easy to shrink into small scurf and fall off; Acetyl glucosamine can normalize the metabolism of surface glycoprotein of keratinocyte and push it to the outside.

4. Whitening - whitening skin, Acetyl glucosamine can inhibit the glycosylation of tyrosinase, thus inhibiting the ripening of tyrosinase and reducing the synthesis of melanin. The synergistic effect with nicotinamide (which can inhibit melanocytes to transfer melanosomes to keratinocytes) can reduce local pigmentation, fade skin spots, reduce skin color deepening and uneven phenomenon caused by ultraviolet rays, and effectively even skin color.

5. Eliminate free radicals - reduce the damage of free radicals to skin, resist wrinkle and aging, and enhance the repairing ability of skin tissue.

Widely used in various skin care formulations: cream, emulsion, mask, raw solution, etc.


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