Dapivirine-d 4 (TMC120-d 4 ) is deuterium labeled Dapivirine. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI) . Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt , Bad and SAPK/JNK activations.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Infection | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Reverse Transcriptase | Products > Signaling Pathways > Apoptosis
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