1,3-Butadiene diepoxide

1,3-Butadiene diepoxide
  • CAS No.:1464-53-5
Other grades of this product :
1,3-Butadiene diepoxide Basic information
Product Name:1,3-Butadiene diepoxide
Synonyms:1,1’-bi(ethyleneoxide);1,1'-Bi[ethylene oxide];1,2:3,4-diepoxy-butan;2,4-diepoxybutane;3,4-Diepoxybutane;alkylepoxides;Bioxiran;Bioxirane
CAS:1464-53-5
MF:C4H6O2
MW:86.09
EINECS:215-979-1
Product Categories:
Mol File:1464-53-5.mol
1,3-Butadiene diepoxide Chemical Properties
Melting point 2-4 °C(lit.)
Boiling point 56-58 °C25 mm Hg(lit.)
alpha 0°(neat)
density 1.113 g/mL at 25 °C(lit.)
vapor pressure 25 mm Hg ( 56 °C)
refractive index n20/D 1.434(lit.)
Fp 114 °F
storage temp. 0-6°C
form neat
Specific Gravity1.1
color Colorless liquid
Water Solubility Soluble in water (1000 g/L).
Merck 14,3676
BRN 79831
CAS DataBase Reference1464-53-5(CAS DataBase Reference)
IARC(Vol. 11, Sup 7) 1987
EPA Substance Registry SystemDiepoxybutane (1464-53-5)
Safety Information
Hazard Codes T+
Risk Statements 45-46-24/25-26-34-10
Safety Statements 53-45-36/37/39-28-26
RIDADR UN 3384 6.1/PG 1
WGK Germany 1
RTECS EJ8225000
8-10-18
TSCA Yes
HazardClass 6.1
PackingGroup II
HS Code 29109000
Hazardous Substances Data1464-53-5(Hazardous Substances Data)
ToxicityLD50 orl-rat: 78 mg/kg AMIHBC 10,61,54
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
1,3-Butadiene diepoxide Usage And Synthesis
Chemical Propertiesclear colorless to very slightly yellow liquid
UsesDiepoxybutane has been used as a research chemical, as a chemical intermediate, as a curing agent for polymers, as a cross-linking agent for textile fabrics, and to prevent microbial spoilage (IARC 1976, HSDB 2009). It has also been used to synthesize erythritol and pharmaceuticals (HSDB 2009). Because of its cross-linking properties, diepoxybutane is used as a test agent in the diagnosis of Fanconi anemia, which is characterized by chromosomal instability (Auerbach et al. 1989).
UsesCuring of polymers; cross-linking of textile fibers; prevention of microbial spoilage
UsesButadiene diepoxide is used as a research chemical, as a chemical intermediate, as a curing agent for polymers, as a cross-linking agent for textile fabrics, and to prevent microbial spoilage. It is also been used to synthesize erythritol and pharmaceuticals.
Uses1,3-Butadiene Diepoxide is used as a substance in the evaluation of anti-diabetic and anti-ulcer potential of selected fresh fruits samples and their GC/MS analysis. Also in the inhibitory potency of 4-carbon alkanes and alkenes towards CYD2E1 activity.
Production MethodsDiepoxybutane is prepared by chlorination of butadiene followed by epoxidation with peracetic acid, with subsequent hydrolysis of the epoxide group and final reepoxidation with caustic.
General DescriptionColorless liquid. Used in curing polymers; crosslinking textile fibers and to prevent spoilage.
Air & Water ReactionsHighly Flammable
Reactivity ProfileEpoxides, such as 1,3-BUTADIENE DIEPOXIDE, are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.
HazardProbable carcinogen; neoplastigen; tumorigenic; poison; mutagen.
Health HazardSevere skin and eye irritant. Accidental minor exposure caused swelling of the eyelids, upper respiratory tract irritation and painful eye irritation 6 hours after exposure.NOTE: The dl- and meso-forms (CAS Registry Numbers 298-18-0 and 564-00-1, respectively) as well as the L(-) form (CAS Registry Number 30031-64-2) have all been determined to be positive animal carcinogens.
Fire HazardWhen heated to decomposition 1,3-BUTADIENE DIEPOXIDE emits acrid smoke and irritating fumes.
Safety ProfileConfirmed carcinogen withexperimental tumorigenic data. Poison by ingestion,inhalation, skin contact, and intraperitoneal routes.Human mutation data reported. A severe skin and eyeirritant. When heated to decomposition it emits acridsmoke and irritat
CarcinogenicityDiepoxybutane is reasonably anticipated to be a human carcinogenbased on sufficient evidence of carcinogenicity from studies in experimental animals.
1,3-Butadiene diepoxide Preparation Products And Raw materials

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