TPE-MI

Overview

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .

Application

Products | Products > Disease Areas > Plasmodium Infection | Products > Disease Areas > Huntington's Disease | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Huntingtin | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-143218
• CAS No.: 1245606-71-6
• Molecular Formula: C31H23NO2
• Molecular Weight: 441.52
• Purity: 98.93%
• Storage: 4°C, protect from light * In solvent : -80°C, 2 years; -20°C, 1 year (protect from light)
• Availability: In-stock

Source

Original product source