V-0219

Overview

V-0219 is an orally active glucagon-like peptide-1 receptor ( GLP-1R ) positive allosteric modulator. V-0219 potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 potentiates glucose-dependent insulin secretion. V-0219 improves glucose handling in normal and diabetic rodents. V-0219 can be used for the research of obesity-associated diabetes.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Type 2 Diabetes | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-143312
• CAS No.: 878453-71-5
• Molecular Formula: C20H25F3N4O2
• Molecular Weight: 410.43
• Purity: 99.90%
• Storage: Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.07 mM); Clear solution
• Availability: In-stock

Source

Original product source