NBTIs-IN-5 (Compound 5r) is a NBTI (Novel Bacterial Topoisomerase Inhibitor) DNA gyrase inhibitor with an IC 50 of 1.5 μM against Mycobacterium abscessus ( Mabs ) DNA gyrase. NBTIs-IN-5 inhibits Mabs bamboo bacterial growth with an MIC 90 of 0.4 μM.
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