HDAC-IN-30 is a novel multi-target HDAC inhibitor, including HDAC1 ( IC 50 =13.4 nM), HDAC2 ( IC 50 =28.0 nM), HDAC3 ( IC 50 =9.18 nM), HDAC6 ( IC 50 =42.7 nM), HDAC8 ( IC 50 =131 nM). HDAC-IN-30 exhibits potent antitumor efficacy.
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