Pyridone 6 (Standard) is the analytical standard of Pyridone 6. This product is intended for research and analytical applications. Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2 , 5 nM for JAK3 , and 15 nM for JAK1 , while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases .
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