SGC-SMARCA-BRDVIII

Overview

SGC-SMARCA-BRDVIII, a chemical probe, is a potent and selective inhibitor of SMARCA2/4 and PB1(5) , with K d s of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3) , with K d s of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-145446
• CAS No.: 1997319-84-2
• Molecular Formula: C19H25N5O3
• Molecular Weight: 371.43
• Purity: 99.66%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution
• Availability: In-stock

Source

Original product source