17(R)-Resolvin D1 methyl ester is the methyl ester of Resolvin D1 (RvD1) ( HY-125527 ) induced by Aspirin ( HY-14654 ) with the 17R epimer (AT-RvD1). RvD is a regulator of transendothelial migration of human polymorphonuclear leukocytes and an anti-inflammatory agent. The 17R-trihydroxy-4Z of RvD1 also blocks transendothelial migration of human neutrophils ( EC 50 approximately 30 nM). AT-RvD1 is an effective form that protects against the rapid inactivation of Resolvin D1 .
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Endogenous Metabolite
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