EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC 50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC 50 >56.2 μM).
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