Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs) , with IC 50 s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1 , ImiS , IMP-1 and VIM-2 , respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity.
Products | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Bacterial
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