HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC 50 s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC 50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS.
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