Mtb ATP synthase-IN-1 (compound 6ab) is a potent Mycobacterium tuberculosis ( Mtb ) ATP synthase inhibitor, with MIC of 0.452-0.499 μg/mL against Mtb . Mtb ATP synthase-IN-1 has good metabolic stability, low cytotoxicity (Vero IC 50 > 64 μg/mL), and acceptable oral bioavailability. Mtb ATP synthase-IN-1 can be used for researching anti-mycobacterium.
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