PROTAC EGFR degrader 6 is a PROTAC-based degrader and inducer targeting EGFRdel19 . PROTAC EGFR degrader 6 induces the degradation of EGFRdel19 via the ubiquitin-proteasome system. PROTAC EGFR degrader 6 induces apoptosis . PROTAC EGFR degrader 6 arrests cells at the G1 phase. PROTAC EGFR degrader 6 can be used in research related to non-small cell lung cancer . (Pink: EGFR Target protein ligand; Blue: Cereblon ligand ( HY-A0003 ); Black: linker).
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Apoptosis
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