HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC 50 s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC 50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent.
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