Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC 50 value of 1.5 µM, an MIC value of 4.5 µM, an IC 90 value of 2.5 µM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv . Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity.
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