JAK3-IN-12 (compound 5k) is a highly potent JAK3 inhibitor with IC 50 values of 9.5 nM, 18 nM and 42 nM for JAK3 , JAK1 and JAK2 , respectively. JAK3-IN-12 can be used for researching rheumatoid arthritis.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > JAK
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