Thalidomide -O-C6-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide ( HY-14658 ) based cereblon ligand and a linker used in PROTAC technology. Thalidomide -O-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis
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