Ent-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime ( HY-B0593 ), rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC 50 value of rel-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid ( HY-A0256 ) and Ticarcillin ( HY-139805 ), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes .
Products | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Bacterial
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