ASM-IN-1

Overview

ASM-IN-1 is a potent and orally active acid sphingomyelinase (ASM) inhibitor with an IC 50 value of 1.5 µM. ASM-IN-1 reduces lipid plaques in the aortic arch and aorta and reduces plasma ceramide concentration and Ox-LDL levels. ASM-IN-1 shows antiatherosclerotic and anti-inflammatory activity.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Phospholipase

Product Information

• Catalog No.: HY-149120
• CAS No.: 2913151-46-7
• Molecular Formula: C16H12BrN3O4
• Molecular Weight: 390.19
• Purity: 98.65%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 3 mg/mL (7.69 mM); Clear solution
• Availability: In-stock

Source

Original product source