Incadronic acid

Overview

Incadronic acid inhibits growth of Dictyostelium discoideum with an IC 50 of 1.6 μM. Incadronic acid binds the farnesyl diphosphate synthase ( FPPS ) in Leishmania major with the K i of 23 nM. Incadronic acid inhibits the bone resorption and reduces bone loss, that can be used in osteoporosis research. Incadronic acid inhibits the proliferation of cells RAW264.7, PC-3 and MCF-7 with IC 50 of 48 to 228.6 µM.

Application

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Product Information

• Catalog No.: HY-149149
• CAS No.: 124351-85-5
• Molecular Formula: C8H19NO6P2
• Molecular Weight: 287.19
• Purity: 98.03%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.25 mg/mL (4.35 mM); Clear solution
• Availability: In-stock

Source

Original product source