JAK1-IN-12 is a selective inhibitor of JAK1 , with IC 50 of 0.0246 μM. And IC 50 s of 0.423 μM, 0.410 μM and 1.12 μM for JAK2 , JAK3 and TYK2 . JAK1-IN-12 promotes hair growth in mice. JAK1-IN-12 can be used for research of immune and inflammatory diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > JAK
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