Antileishmanial agent-16 (compound 14c) is an anti- Leishmania agent. Antileishmanial agent-16 has superior anti- Leishmania major promastigotes activity ( IC 50 = 0.59 µM) and anti- Leishmania major amastigotes activity ( IC 50 = 0.81 µM). Antileishmanial agent-16 has good safety to mammalian cells (VERO cells).
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