IMA-1 is an inhibitor that inhibits the interaction between arachidonic acid 12-lipoxygenase ( ALOX12 ) and acetyl-CoA carboxylase 1 ( ACC1 ). IMA-1 significantly blocks the progression of diet-induced non-alcoholic steatohepatitis (NASH) in male mice and crab-eating monkeys, and does not cause hyperlipidemia. IMA-1 can be used for the study of NASH.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > Acetyl-CoA Carboxylase
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