XF056-132

Overview

XF056-132 (MS132N TFA) is an inactive WDR5 PROTAC degrader with a K d value of 106 nM against human targets, and exhibits no significant binding to the VHL complex, serves as a negative control for MS132. XF056-132 binds to WDR5 , does not induce WDR5 degradation in pancreatic cancer cells, and exerts no inhibitory effect on adenocarcinoma cells. XF056-132 can be used in the research of pancreatic ductal adenocarcinoma. (Pink: WDR5 ligand ( HY-141799 ); Blue: Ligands for E3 Ligase ligand ( HY-125845 ); Black: linker).

Application

Products | Products > Disease Areas > Pancreatic Ductal Adenocarcinoma | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > WDR5

Product Information

• Catalog No.: HY-150400A
• CAS No.: 2694057-55-9
• Molecular Formula: C53H58F7N9O9S
• Molecular Weight: 1130.14
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source