FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
  • CAS No.:2241669-84-9
  • Grade:98.85%
  • Formula:C27H39FN8O6S
  • M.W.:622.71
  • Solvent:≥ 2.5 mg/mL (4.01 mM); Clear solution

Overview

FBnG -(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC4 ( HY-134640 ) that incorporates a degradation tag FBnG ( HY-W073762 ) and a glycol linker. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > AUTACs

Product Information

  • Catalog No.: HY-150408
  • CAS No.: 2241669-84-9
  • Molecular Formula: C27H39FN8O6S
  • Molecular Weight: 622.71
  • Purity: 98.85%
  • Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
  • Solubility: ≥ 2.5 mg/mL (4.01 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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