CHMFL-PI4K-127 (compound 15g) is an orally active, potent and high selective PfPI4K ( Plasmodium falciparum PI4K kinase) inhibitor, with an IC 50 of 0.9 nM. CHMFL-PI4K-127 exhibits potent activity against 3D7 Plasmodium falciparum , with an EC 50 of 25.1 nM. CHMFL-PI4K-127 shows antimalaria efficacy.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Infection | Products > Signaling Pathways > PI4K | Products > Signaling Pathways > PI3K
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