MMT5-14 is a remdesivir analogue with a higher antiviral activity in four variants of SARS-CoV-2 than Remdesivir ( HY-104077 ). MMT5-14 inhibits SARS-CoV-2, α, β, γ and δ variants with EC 50 s of 0.4, 2.5, 15.9, 1.7 and 5.6 μM, respectively. MMT5-14 can be used for the research of COVID-19.
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