(Rac)-Lonafarnib

(Rac)-Lonafarnib
  • CAS No.:193275-86-4
  • Grade:99.98%
  • Formula:C27H31Br2ClN4O2
  • M.W.:638.82

Overview

(Rac)-Lonafarnib (Sch66336 racemate) is the racemate of Lonafarnib. Lonafarnib is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras , K-ras and N-ras with IC 50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Farnesyl Transferase

Product Information

  • Catalog No.: HY-15136B
  • CAS No.: 193275-86-4
  • Molecular Formula: C27H31Br2ClN4O2
  • Molecular Weight: 638.82
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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