Chitin synthase inhibitor 5 (compound 9a) is an inhibitor of chitin synthase with an IC 50 value of 0.14 mM. Chitin synthase inhibitor 5 shows broad-spectrum antifungal activity in vitro and shows good inhibition to C. albicans , A. flavus , A. fumigatus and C. neoformans . Chitin synthase inhibitor 5 can be used for the research of fungal .
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