SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent M pro inhibitor ( IC 50 =0.40 μM) with good anti-SARS-CoV-2 activity ( EC 50 =1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies.
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