ACBI2 is a highly potent and orally active VHL PROTAC SMARCA2 degrader ( EC 50 : 7 nM), which selectively degrades SMARCA2 with a DC 50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer .
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex
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