Pyridostatin hydrochloride

Overview

Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent ( K d =490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src . Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Src | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > G-quadruplex | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-15176A
• CAS No.: 1781882-65-2
• Molecular Formula: C31H37Cl5N8O5
• Molecular Weight: 778.94
• Purity: 99.95%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: 100 mg/mL (128.38 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source