TD1092 is a pan- IAP degrader, degrades cIAP1 , cIAP2 , and XIAP . TD1092 activates Caspase 3/7, and promotes cancer cells apoptosis via IAP degradation. TD1092 inhibits TNFα mediated NF-κB pathway and reduces the phosphorylation of IKK , IkBα, p65, and p38. TD1092 can act as PROTAC , and is used for cancer research.
Products | Products > Disease Areas > Triple-Negative Breast Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > IAP | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > PANoptosis
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