STING agonist-25 (CF505) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , increases phosphorylation of STING , TBK1 and IRF3 . STING agonist-23 promotes the levels of IFN-β , IL-6 , CXCL-10 , TNF-α , ISG-15 , and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains.
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