GalNAc-L96 free base is a conjugate of GalNAc and its ligand L96. When conjugated with the A-rich HCV sequence (H12), GalNAc-L96 free base binds potently to ASGPR , with a K i value of 10.4 nM. GalNAc-L96 free base promotes siRNA delivery to hepatocytes.
Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Asialoglycoprotein Receptor (ASGPR) | Products > Signaling Pathways > Small Interfering RNA (siRNA)
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