Hi 76-0079 (NNC0076-0079; 76-0079) is a lipase inhibitor that specifically targets hormone-sensitive lipase ( HSL ). Hi 76-0079 inhibits PNPB Hydrolysis in cell lysates of HEK293A cells overexpressing Lipe with an IC 50 value of 0.1 μM. Hi 76-0079 synergizes with the ATGL inhibitor Atglistatin ( HY-15859 ) to block lipolysis in vitro. Hi 76-0079 can be used for the study of lipid metabolism.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Lipase
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