Sacubitril

Sacubitril
  • CAS No.:149709-62-6
  • Grade:99.92%
  • Formula:C24H29NO5
  • M.W.:411.49
  • Solvent:≥ 2.5 mg/mL (6.08 mM); Clear solution

Overview

Sacubitril (AHU-377) is a potent and orally active NEP ( neprilysin ) inhibitor with an IC 50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Neprilysin

Product Information

  • Catalog No.: HY-15407
  • CAS No.: 149709-62-6
  • Molecular Formula: C24H29NO5
  • Molecular Weight: 411.49
  • Purity: 99.92%
  • Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.5 mg/mL (6.08 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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