13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the main metabolite of Tacrolimus ( HY-13756 ). 13-O-Desmethyl tacrolimus has a weak immunosuppressive activity. 13-O-Desmethyl tacrolimus is mainly used in the research on monitoring Tacrolimus ( HY-13756 ) by monitoring the ratio of 13-DMT/Tacrolimus.
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