S0859 is a selective, high-affinity generic Na + /HCO 3 - transporter ( NBC ) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (K i =1.7 μM, full inhibition at approximately 30 μM).
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Na+/HCO3- Cotransporter
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