SCH900776

Overview

SCH900776 (MK-8776) is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 ( Chk1 ) with an IC 50 of 3 nM. SCH900776 shows 50- and 500-fold selectivity over CDK2 and Chk2 , respectively.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Checkpoint Kinase (Chk)

Product Information

• Catalog No.: HY-15532
• CAS No.: 891494-63-6
• Molecular Formula: C15H18BrN7
• Molecular Weight: 376.25
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (6.64 mM); Clear solution
• Availability: In-stock

Source

Original product source