FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS ( HY-D1056 ) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6 . FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway.
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