Metallo-β-lactamase-IN-11 (compound 5f) is a Metallo-β-lactamases ( MBLs ) inhibitor, potent against bacterial metallophyllactamase CphA ( IC 50 =45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Bacterial
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