Cisd2 agonist 2

Overview

Cisd2 agonist 2 (compound 6) is a Cisd2 activator ( EC 50 =191 nM), and Cisd2 levels are associated with non-alcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant in vivo toxicity in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout). Cisd2 (CDGSH iron sulfur domain 2) is a zinc finger protein that is mainly localized in the endoplasmic reticulum or mitochondrial membrane. Cisd2 participates in mitochondrial function by forming homodimers containing two redox-active 2Fe-2S clusters.

Application

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Product Information

• Catalog No.: HY-155539
• CAS No.: 2916371-59-8
• Molecular Formula: C14H14N2O4S
• Molecular Weight: 306.34
• Purity: 99.17%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (8.16 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source