JNK-1-IN-2 (Compound c6) is a JNK-1 inhibitor ( IC 50 : 33.5 nM). JNK-1-IN-2 also inhibits JNK-2 and JNK-3 with IC 50 s of 112.9 nM and 33.2 nM. JNK-1-IN-2 inhibits the phosphorylation of c-Jun . JNK-1-IN-2 reverses lung impairment. JNK-1-IN-2 can be used for research of pulmonary fibrosis.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > JNK
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